Floatz Rating
BB68/100
Confidence
Indicative
Sponsor
Ospedale di Camposampiero
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
74High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06252662CT.gov Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies | — | Recruiting | — | — | — |
NCT06574022CT.gov Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks | — | Recruiting | — | — | — |
NCT05727098CT.gov Dexmedetomedine and Ketamine in Erector Spinae Block for Postoperative Analgesia Following Mastectomy. | — | Completed | — | — | — |
NCT07081581CT.gov Analgesic Effect of Serratus Plane Block With Adjuvant Agents in Breast Cancer Surgery | — | Completed | — | — | — |
NCT05232084CT.gov Different Volumes of Erector Spinae Plane Block for Breast Surgery | — | Completed | — | — | — |
NCT04429893CT.gov Magnesium Sulphate to Bupivicaine in Serratus Anterior Plane Block in Modified Radical Mastectomy | — | Unknown | — | — | — |
NCT04603911CT.gov RCT Comparing ESPB Solutions in Breast Surgery | — | Completed | — | — | — |
NCT04336917CT.gov Ultrasound Guided Rhomboid Intercostal and Subserratus Plane Block in Breast Cancer Surgeries | — | Completed | — | — | — |
NCT04019834CT.gov Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy | — | Completed | — | — | — |
NCT04218149CT.gov Serratus Plane Block vs Erector Spinae Plane Block on Postoperative Analgesia in Patients Undergoing Unilateral Breast Surgery | — | Completed | — | — | — |
Show 17 more trialsShow fewer
NCT02822196CT.gov Serratus Anterior Muscle Plane Block vsThoracic Paravertebral Block For Unilateral Mastectomies | — | Withdrawn | — | — | — |
NCT03388814CT.gov Speeding Recovery From Pain and Opioid Use | — | Withdrawn | — | — | — |
NCT03393117CT.gov Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction | — | Withdrawn | — | — | — |
NCT04238377CT.gov Post Mastectomy Pain Syndrome After Preoperative Stellate Ganglion Block for Breast Cancer Surgeries | — | Unknown | — | — | — |
NCT03538483CT.gov Erector Spinae Plane Block Versus Serratus Plane Block for Breast Surgery | — | Completed | — | — | — |
NCT03351348CT.gov Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control | — | Recruiting | — | — | — |
NCT03360214CT.gov PEMF and PEC Blocks in Mastectomy Reconstruction Patients | — | Completed | — | — | — |
NCT03084536CT.gov PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery | — | Completed | — | — | — |
NCT03063073CT.gov Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block | — | Completed | — | — | — |
NCT02897934CT.gov CWI and Discharge After Breast Cancer Surgery | — | Completed | — | — | — |
NCT02336529CT.gov Nerveblocks for Persistent Pain After Breast Cancer Surgery | — | Unknown | — | — | — |
NCT03799757CT.gov Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain | — | Completed | — | — | — |
NCT02525718CT.gov Selective Intraoperative Administration of Local Anesthesia in Breast Reconstruction | — | Completed | — | — | — |
NCT02659501CT.gov Liposomal Bupivacaine in Implant Based Breast Reconstruction | — | Terminated | — | — | — |
NCT02495363CT.gov Analgesic Effects of Ultrasound Guided PEC Blocks on Analgesic Opioid Consumption of Cancer Surgery Patients | — | Completed | — | — | — |
NCT01314144CT.gov Use of Continuous Wound Infusion of Bupivacaine for Analgesia Following Axillary Clearance Surgery | — | Unknown | — | — | — |
NCT00547989CT.gov Paravertebral Block, an Adjunct to General Anaesthesia for Breast Surgery? | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Breast Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Marcaine (this asset) | Ospedale di Camposampiero | Approved | BB · 68 |
| Darolutamide | Vandana Abramson | P2 | BBB |
| Pertuzumab | SWOG Cancer Research Network | P4 | BB |
| Palbociclib | Hoffmann-La Roche | P4 | BB |
| Trastuzumab Duocarmazine | Byondis B.V. | P3 | BB |
| Goserelin | TerSera Therapeutics LLC | P4 | BB |
| Ribociclib | National Cancer Institute (NCI) | P4 | BB |
| Oxaliplatin | Beijing Biostar Pharmaceuticals Co., Ltd. | P4 | BB |
| Eribulin Monomethanesulfonate | Henan Cancer Hospital | P4 | BB |
+42 more in the Breast Cancer cohort
Other indications for Marcaine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Migraine Disorder | — | P4 | BBB · 74 |
| Neuralgia | — | P4 | BBB · 74 |
| Headache Disorder | — | P4 | BBB · 73 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Marcaine in Breast Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/1-butyl-26-pipecoloxylidide-monohydrochloride-breast-cancer
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →