Floatz Rating
BB67/100
Confidence
Indicative
Sponsor
Shirong Tan
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
58Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06959147CT.gov High-Voltage Long-Duration Pulsed Radiofrequency Combined With Liposomal Bupivacaine Subcutaneous Block for Herpes Zoster-Associated Neuralgia | — | Recruiting | — | — | — |
NCT05517486CT.gov Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects | — | Unknown | — | — | — |
NCT00478179CT.gov Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Postherpetic Neuralgia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Marcaine (this asset) | Shirong Tan | Approved | BB · 67 |
| Lidocaine | Seoul National University Hospital | P4 | BBB |
| Pregabalin | Neurodawn Pharmaceutical Co., Ltd. | P4 | BBB |
| Gabapentin | University of Medicine and Pharmacy at Ho Chi Minh City | P4 | BBB |
| Capsaicin | Astellas Pharma Europe Ltd. | P4 | BBB |
| (±)-Tramadol | Astellas Pharma Inc | P4 | BB |
| Crisugabalin | Haisco Pharmaceutical Group Co., Ltd. | P3 | BB |
| Eslicarbazepine Acetate | Bial - Portela C S.A. | P3 | BB |
| Etoricoxib | Analgesic Solutions | P4 | BB |
+42 more in the Postherpetic Neuralgia cohort
Other indications for Marcaine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Migraine Disorder | — | P4 | BBB · 74 |
| Neuralgia | — | P4 | BBB · 74 |
| Headache Disorder | — | P4 | BBB · 73 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Marcaine in Postherpetic Neuralgia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/1-butyl-26-pipecoloxylidide-monohydrochloride-postherpetic-neuralgia
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