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[177lu]lu-akir001

Poorly Differentiated Thyroid Gland Carcinoma

Explore 6 assets in Poorly Differentiated Thyroid Gland Carcinoma
Floatz Rating
C39/100
Confidence
Indicative
v0.2
Sponsor
Karolinska University Hospital
Modality
radiopharmaceutical
Development Phase
Early Phase 1
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
24Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
[177Lu]Lu-AKIR001 First-in-human Study
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Poorly Differentiated Thyroid Gland Carcinoma

AssetSponsorPhaseRating
[177lu]lu-akir001 (this asset)Karolinska University HospitalEarly P1C · 39
CyclophosphamideM.D. Anderson Cancer CenterP2CCC
FludarabineM.D. Anderson Cancer CenterP2CCC
LifileucelM.D. Anderson Cancer CenterP2CCC
IpilimumabM.D. Anderson Cancer CenterP2CCC
NivolumabM.D. Anderson Cancer CenterP2CCC
GefitinibNational Cancer Institute (NCI)N/ANR

Other indications for [177lu]lu-akir001

IndicationSponsorPhaseRating
Cervical CarcinomaEarly P1C · 39
Vulvar CarcinomaEarly P1C · 39
Thyroid Gland Undifferentiated (Anaplastic) CarcinomaEarly P1C · 39

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. [177lu]lu-akir001 in Poorly Differentiated Thyroid Gland Carcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/177lulu-akir001-poorly-differentiated-thyroid-gland-carcinoma

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