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Floatz Rating
CCC54/100
Confidence
Indicative
v0.2
Sponsor
John M. Buatti
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
39Moderate confidence
Detailed axis rationale is planned and will be published soon.

No trial-level evidence is linked to this axis yet.

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Anus Neoplasm

AssetSponsorPhaseRating
18f-flt (this asset)John M. BuattiP2CCC · 54
FluorouracilumJessa HospitalP4BB
v503Merck Sharp & Dohme LLCP3BB
CapecitabineBlokhin's Russian Cancer Research CenterP3B
MitomycinsBlokhin's Russian Cancer Research CenterP3B
Aijp (Arnebia Indigo Jade Pearl)University of California, San FranciscoP2B
Vgx-3100Inovio PharmaceuticalsP2B
EnzalutamideMacroGenicsP2CCC
AbirateroneMacroGenicsP2CCC

+4 more in the Anus Neoplasm cohort

Other indications for 18f-flt

IndicationSponsorPhaseRating
Acute Lymphoblastic LeukemiaP2B · 62
Breast CarcinomaP2B · 58
Non-Small Cell Lung CarcinomaP2CCC · 55

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. 18f-flt in Anus Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/18f-flt-anus-neoplasm

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