19-28z/il-18 car t cells
B-Lymphoblastic Leukemia/Lymphoma With T(9;22)(Q34.1;Q11.2)
Explore 31 assets in B-Lymphoblastic Leukemia/Lymphoma With T(9;22)(Q34.1;Q11.2) →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Memorial Sloan Kettering Cancer Center
Modality
Cell therapy
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06287528CT.gov A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL) | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · B-Lymphoblastic Leukemia/Lymphoma With T(9;22)(Q34.1;Q11.2)
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| 19-28z/il-18 car t cells (this asset) | Memorial Sloan Kettering Cancer Center | P1 | CC · 43 |
| Nilotinib | The University of Hong Kong | P2 | BBB |
| Blinatumomab | Novartis Pharmaceuticals | P3 | BBB |
| Cytarabine | Novartis Pharmaceuticals | P3 | BBB |
| Imatinib | The University of Hong Kong | P3 | BB |
| Dasatinib | SWOG Cancer Research Network | P3 | BB |
| Olverembatinib | Institute of Hematology & Blood Diseases Hospital, China | P3 | BB |
| Methotrexate | Novartis Pharmaceuticals | P3 | BB |
| (+)-Vincristine | Novartis Pharmaceuticals | P2 | BB |
+39 more in the B-Lymphoblastic Leukemia/Lymphoma With T(9;22)(Q34.1;Q11.2) cohort
Other indications for 19-28z/il-18 car t cells
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Lymphoblastic Leukemia | — | P1 | CC · 43 |
| Adult Acute Lymphoblastic Leukemia | — | P1 | CC · 43 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. 19-28z/il-18 car t cells in B-Lymphoblastic Leukemia/Lymphoma With T(9;22)(Q34.1;Q11.2). Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/19-28zil-18-car-t-cells-b-lymphoblastic-leukemialymphoma-with-t922q341q112
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