4,5,7,4',5',7'-HEXAHYDROXY-2,2'-DIMETHYLNAPHTHODIANTHRONE
Mycosis Fungoides
Explore 48 assets in Mycosis Fungoides →Floatz Rating
BB66/100
Confidence
Indicative
Sponsor
Soligenix
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
52High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06470451CT.gov Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL | — | Recruiting | — | — | — |
NCT06149247CT.gov HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL | — | Completed | — | — | — |
NCT05872854CT.gov Treatment of Mycosis Fungoides With Hypericin Ointment and Visible Light | — | Completed | — | — | — |
NCT05380635CT.gov PK and ECG Determinations Following 8 Weeks of HyBryte Treatment for Cutaneous T-Cell Lymphoma | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Mycosis Fungoides
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| 4,5,7,4',5',7'-HEXAHYDROXY-2,2'-DIMETHYLNAPHTHODIANTHRONE (this asset) | Soligenix | P3 | BB · 66 |
| (+)-Vincristine | Virogen Biotechnology Inc. | P4 | BBB |
| Cyclophosphamide | National Cancer Institute (NCI) | P4 | BBB |
| Fludarabine | National Cancer Institute (NCI) | P2 | BBB |
| Nivestim | Mayo Clinic | P4 | BBB |
| Adriamycin | Pierluigi Porcu | P4 | BBB |
| Etoposide | Fred Hutchinson Cancer Center | P2 | BBB |
| Dexasone | City of Hope Medical Center | P2 | BBB |
| Cediranib | National Cancer Institute (NCI) | P2 | BB |
+42 more in the Mycosis Fungoides cohort
Other indications for 4,5,7,4',5',7'-HEXAHYDROXY-2,2'-DIMETHYLNAPHTHODIANTHRONE
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | — | P3 | BB · 69 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. 4,5,7,4',5',7'-HEXAHYDROXY-2,2'-DIMETHYLNAPHTHODIANTHRONE in Mycosis Fungoides. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/457457-hexahydroxy-22-dimethylnaphthodianthrone-mycosis-fungoides
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