Floatz Rating
CCC50/100
Confidence
Indicative
Sponsor
Peking Union Medical College Hospital
Modality
radiopharmaceutical
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
35Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05034783CT.gov [68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients | — | Unknown | — | — | — |
NCT04979611CT.gov The Clinical Application of 68Ga-NOTA-exendin-4 PET/CT in Detecting Insulinoma | — | Unknown | — | — | — |
NCT02560376CT.gov 68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis | — | Unknown | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Pancreatic Insulinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| [68ga]ga-nota-exendin-4 (this asset) | Peking Union Medical College Hospital | P1 | CCC · 50 |
| Capecitabine | Vanderbilt-Ingram Cancer Center | P2 | BB |
| Everolimus | Emory University | P2 | B |
| Sorafenib | National Cancer Institute (NCI) | P2 | B |
| Regorafenib | University of Southern California | P2 | B |
| Pazopanib | National Cancer Institute (NCI) | P2 | B |
| Temsirolimus | National Cancer Institute (NCI) | P2 | B |
| Gefitinib | National Cancer Institute (NCI) | P2 | B |
| Romidepsin | National Cancer Institute (NCI) | P2 | CCC |
+13 more in the Pancreatic Insulinoma cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. [68ga]ga-nota-exendin-4 in Pancreatic Insulinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/68gaga-nota-exendin-4-pancreatic-insulinoma
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