99mtc-p5+14 is an amyloid reactive peptide labeled with technetium-99m.
Primary Systemic Amyloidosis
Explore 10 assets in Primary Systemic Amyloidosis →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
University of Tennessee Graduate School of Medicine
Modality
radiopharmaceutical
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05951816CT.gov A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis | — | Unknown | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Primary Systemic Amyloidosis
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| 99mtc-p5+14 is an amyloid reactive peptide labeled with technetium-99m. (this asset) | University of Tennessee Graduate School of Medicine | P1 | CC · 43 |
| Adriamycin | Margarida Magalhaes-Silverman | P2 | B |
| Dexasone | Margarida Magalhaes-Silverman | P2 | B |
| Melphalan | Margarida Magalhaes-Silverman | P2 | B |
| Bortezomib | Margarida Magalhaes-Silverman | P2 | B |
| Cyclophosphamide | Margarida Magalhaes-Silverman | P2 | B |
| Cis-Diamminedichloroplatinum Ii | Margarida Magalhaes-Silverman | P2 | B |
| Etoposide | Margarida Magalhaes-Silverman | P2 | B |
| Evuzamitide | University of Tennessee Graduate School of Medicine | P1/2 | B |
+16 more in the Primary Systemic Amyloidosis cohort
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. 99mtc-p5+14 is an amyloid reactive peptide labeled with technetium-99m. in Primary Systemic Amyloidosis. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/99mtc-p514-is-an-amyloid-reactive-peptide-labeled-with-technetium-99m-primary-systemic-amyloidosis
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