Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
UniQure Biopharma B.V.
Modality
gene_therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06063850CT.gov AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Temporal Lobe Epilepsy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| aav9-hsyn1-migrik2 (this asset) | UniQure Biopharma B.V. | P1/2 | CCC · 48 |
| Nrtx-1001 | Neurona Therapeutics | P3 | BB |
| Naluzotan | National Institute of Neurological Disorders and Stroke (NINDS) | P2 | CCC |
| Ferumoxytol | University of Alberta | P2 | CCC |
| Ux-Gip001 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Early P1 | C |
| Florbetaben | University of Minnesota | Unk | D |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. aav9-hsyn1-migrik2 in Temporal Lobe Epilepsy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/aav9-hsyn1-migrik2-temporal-lobe-epilepsy
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