Abemaciclib
Digestive System Neuroendocrine Tumor, Grade 1/2
Explore 6 assets in Digestive System Neuroendocrine Tumor, Grade 1/2 →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
University of Washington
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT03891784CT.gov Abemaciclib in Treating Patients With Advanced, Refractory, and Unresectable Digestive System Neuroendocrine Tumors | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Digestive System Neuroendocrine Tumor, Grade 1/2
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Abemaciclib (this asset) | University of Washington | P2 | CCC · 53 |
| Fluorouracilum | Mayo Clinic | P2/3 | BB |
| Irinotecan | National Cancer Institute (NCI) | P3 | BB |
| Oxodotreotide | Vanderbilt-Ingram Cancer Center | P4 | BB |
| L-Cysteinamide, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-N-(2-Hydroxy-1-(Hydroxymethyl)Propyl)-, Cyclic (2->7)-Disulfide, (R-(R*,R*))- | National Cancer Institute (NCI) | P3 | BB |
| Temsirolimus | National Cancer Institute (NCI) | P2 | BB |
| Oxaliplatin | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | P2/3 | BB |
| Carboplatin | National Cancer Institute (NCI) | P2 | BB |
| Cyclophosphamide | Children's Oncology Group | P2 | B |
+35 more in the Digestive System Neuroendocrine Tumor, Grade 1/2 cohort
Other indications for Abemaciclib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hormone Receptor-Positive Breast Cancer | — | P4 | BBB · 72 |
| Estrogen-Receptor Positive Breast Cancer | — | P3 | BB · 70 |
| Metastatic Neoplasm | — | P4 | BB · 67 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- FluorouracilumMayo ClinicBB
- IrinotecanNational Cancer Institute (NCI)BB
- OxodotreotideVanderbilt-Ingram Cancer CenterBB
- L-Cysteinamide, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-N-(2-Hydroxy-1-(Hydroxymethyl)Propyl)-, Cyclic (2->7)-Disulfide, (R-(R*,R*))-National Cancer Institute (NCI)BB
- TemsirolimusNational Cancer Institute (NCI)BB
Citation
Floatz Terminal. Abemaciclib in Digestive System Neuroendocrine Tumor, Grade 1/2. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/abemaciclib-digestive-system-neuroendocrine-tumor-grade-12
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