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Acetylcysteine

Mucus Inspissation Of Respiratory Tract

Floatz Rating
BB64/100
Confidence
Indicative
v0.2
Sponsor
Zambon SpA
Modality
Small molecule
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Clinical Trial to Compare the Efficacy and Safety of 1-week Treatment of Intravenous N-acetylcysteine (NAC) 600 mg Twice Daily, Ambroxol Hydrochloride 30 mg Twice Daily and Placebo as Expectorant Therapies in Adult Chinese Patients With Respiratory Tract Diseases and Abnormal Mucus Secretions
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.

Same indication · Mucus Inspissation Of Respiratory Tract

AssetSponsorPhaseRating
Acetylcysteine (this asset)Zambon SpAP3BB · 64
AmbroxolZambon SpAP3BB
gs-9411Gilead SciencesP1NR

Other indications for Acetylcysteine

IndicationSponsorPhaseRating
Idiopathic Pulmonary FibrosisP4BBB · 74
Schizophreniform DisorderP4BBB · 74
Pulmonary FibrosisP3BB · 70

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Acetylcysteine in Mucus Inspissation Of Respiratory Tract. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/acetylcysteine-mucus-inspissation-of-respiratory-tract

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