Adenovirus 5 Cea/Muc1/Brachyury Vaccine Tri-Ad5
Colorectal Neoplasm
Explore 117 assets in Colorectal Neoplasm →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
vaccine
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05419011CT.gov Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Colorectal Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Adenovirus 5 Cea/Muc1/Brachyury Vaccine Tri-Ad5 (this asset) | National Cancer Institute (NCI) | P2 | CCC · 53 |
| Fluorouracilum | Rutgers, The State University of New Jersey | P4 | BBB |
| Oxaliplatin | Peking University Cancer Hospital & Institute | P4 | BBB |
| Irinotecan | Shanghai Zhongshan Hospital | P4 | BBB |
| Ferric Carboxymaltose [Ferinject] | Nottingham University Hospitals NHS Trust | P4 | BBB |
| Regorafenib | Sergey Orlov, MD | P4 | BB |
| Capecitabine | Rutgers, The State University of New Jersey | P4 | BB |
| Nivolumab | Bristol-Myers Squibb | P3 | BB |
| Barii Sulfas | London North West Healthcare NHS Trust | P4 | BB |
+41 more in the Colorectal Neoplasm cohort
Other indications for Adenovirus 5 Cea/Muc1/Brachyury Vaccine Tri-Ad5
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Lynch Syndrome | — | P2 | CCC · 53 |
| Colorectal Carcinoma | — | P2 | CCC · 51 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Adenovirus 5 Cea/Muc1/Brachyury Vaccine Tri-Ad5 in Colorectal Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/adenovirus-5-ceamuc1brachyury-vaccine-tri-ad5-colorectal-neoplasm
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