Adenovirus 5/F35-Human Guanylyl Cyclase C-Padre
Digestive System Cancer
Explore 73 assets in Digestive System Cancer →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Thomas Jefferson University
Modality
vaccine
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04111172CT.gov A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Digestive System Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Adenovirus 5/F35-Human Guanylyl Cyclase C-Padre (this asset) | Thomas Jefferson University | P2 | CCC · 53 |
| Irinotecan | Amgen | P2 | BB |
| Dexasone | Cedars-Sinai Medical Center | P4 | BB |
| Fluorouracilum | Alliance for Clinical Trials in Oncology | P2 | BB |
| (±)-2-(O-Chlorophenyl)-2-(Methylamino)Cyclohexanone | Brian Anderson, MD | P4 | BB |
| Marcaine | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | P4 | BB |
| Mlf 541 | B. Braun Melsungen AG | P3 | BB |
| Epinephrine | Cedars-Sinai Medical Center | P4 | BB |
| Durvalumab | M.D. Anderson Cancer Center | P2 | B |
+42 more in the Digestive System Cancer cohort
Other indications for Adenovirus 5/F35-Human Guanylyl Cyclase C-Padre
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Cancer | — | P2 | CCC · 53 |
| Gastric Cancer | — | P2 | CCC · 53 |
| Esophageal Adenocarcinoma | — | P2 | CCC · 53 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Adenovirus 5/F35-Human Guanylyl Cyclase C-Padre in Digestive System Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/adenovirus-5f35-human-guanylyl-cyclase-c-padre-digestive-system-cancer
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