Floatz Rating
D30/100
Confidence
Indicative
Sponsor
Emory University
Modality
protein_peptide
Development Phase
N/A
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01319851CT.gov Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Chediak-Higashi Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Alefacept (this asset) | Emory University | N/A | D · 30 |
| Melphalan | Washington University School of Medicine | P2 | B |
| Alemtuzumab | Washington University School of Medicine | P2 | B |
| Fludarabine | Washington University School of Medicine | P2 | B |
| Thiotepa | Washington University School of Medicine | P2 | CCC |
| Methotrexate | Children's Hospital Los Angeles | P1/2 | CCC |
| Cyclosporin A | Children's Hospital Los Angeles | P1/2 | CCC |
| Abatacept Recombinant | Emory University | P1 | CC |
| Busulfanum | Masonic Cancer Center, University of Minnesota | N/A | D |
+6 more in the Chediak-Higashi Syndrome cohort
Other indications for Alefacept
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Lymphoma | — | P1 | CC · 40 |
| Thalassemia | — | N/A | D · 30 |
| Glanzmann Thrombasthenia | — | N/A | D · 30 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Alefacept in Chediak-Higashi Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/alefacept-chediak-higashi-syndrome
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