Alnugranogene Aldeparvovec
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1
Explore 1 assets in Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1 →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
Passage Bio, Inc.
Modality
gene_therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04747431CT.gov A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Alnugranogene Aldeparvovec (this asset) | Passage Bio, Inc. | P1/2 | CCC · 48 |
Other indications for Alnugranogene Aldeparvovec
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Frontotemporal Dementia | — | P1/2 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Citation
Floatz Terminal. Alnugranogene Aldeparvovec in Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/alnugranogene-aldeparvovec-frontotemporal-dementia-andor-amyotrophic-lateral-sclerosis-1
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