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Alpelisib

Pancreatic Neuroendocrine Neoplasm

Explore 7 assets in Pancreatic Neuroendocrine Neoplasm
Floatz Rating
CC47/100
Confidence
Indicative
v0.2
Sponsor
Novartis Pharmaceuticals
Modality
Small molecule
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Pancreatic Neuroendocrine Neoplasm

AssetSponsorPhaseRating
Alpelisib (this asset)Novartis PharmaceuticalsP1CC · 47
LanreotideFederation Francophone de Cancerologie DigestiveP2/3B
SurvaxmRoswell Park Cancer InstituteP2CCC
SargramostimRoswell Park Cancer InstituteP2CCC
IfaRoswell Park Cancer InstituteP2CCC
Immunoglobulin G1, Anti-(Humanized Mouse Monoclonal Hr3 .Beta.1 Chain Anti-Human Epidermal Growth Factor Receptor), Disulfide With Humanized Mouse Monoclonal Hr3 .Kappa.-Chain, DimerFudan UniversityP2CCC
EverolimusNovartis PharmaceuticalsP1CC
ExemestaneNovartis PharmaceuticalsP1CC
GefitinibShanghai General Hospital, Shanghai Jiao Tong University School of MedicineUnkD

+2 more in the Pancreatic Neuroendocrine Neoplasm cohort

Other indications for Alpelisib

IndicationSponsorPhaseRating
Triple-Negative Breast CarcinomaP3BB · 67
Breast CancerP4BB · 66
HER2 Positive Breast CarcinomaP3BB · 66

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Alpelisib in Pancreatic Neuroendocrine Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/alpelisib-pancreatic-neuroendocrine-neoplasm

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