Floatz Rating
B63/100
Confidence
Indicative
Sponsor
Life Recovery Systems
Modality
protein_peptide
Development Phase
Phase 3
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
48High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02453373CT.gov Helping Stroke Patients With ThermoSuit Cooling | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Brain Ischemia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Alteplase (this asset) | Life Recovery Systems | P3 | B · 63 |
| Dipyridamole | UMC Utrecht | P4 | BB |
| Aspirin | City Clinical Hospital No. 67, Moscow, Russia | P4 | BB |
| Sovateltide | Pharmazz, Inc. | P3 | BB |
| Probucol | Asan Medical Center | P4 | BB |
| Cilostazol | Asan Medical Center | P4 | BB |
| Lacosamide | University of North Carolina, Chapel Hill | P4 | BB |
| 3-N-BUTYLPHTHALIDE | Qianfoshan Hospital | P4 | BB |
| Valproic Acid | University of North Carolina, Chapel Hill | P4 | BB |
+28 more in the Brain Ischemia cohort
Other indications for Alteplase
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Ischemic Stroke | — | P4 | BB · 70 |
| Stroke Disorder | — | P4 | BB · 70 |
| Brain Infarction | — | P4 | BB · 68 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Alteplase in Brain Ischemia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 13, 2026. https://terminal.floatz.ai/assets/alteplase-brain-ischemia
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