Floatz Rating
CC42/100
Confidence
Indicative
Sponsor
Noorik Biopharmaceuticals AG
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
27Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06256432CT.gov Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Kidney Injury
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ambrisentan (this asset) | Noorik Biopharmaceuticals AG | P2 | CC · 42 |
| Angiotensin Ii | The Cleveland Clinic | P4 | BB |
| Gabapentin | Tanta University | P4 | B |
| Everolimus | MARIO ABBUD FILHO | P4 | B |
| Noradrenaline | University of California, Los Angeles | P4 | B |
| Normal Human Serum Albumin | Institute of Liver and Biliary Sciences, India | P3 | B |
| Apsolol | Taipei Veterans General Hospital, Taiwan | P4 | B |
| Dextran 40 For Injection | Ramathibodi Hospital | P2/3 | B |
| Conestat Alfa | University Hospital, Basel, Switzerland | P2 | B |
+22 more in the Acute Kidney Injury cohort
Other indications for Ambrisentan
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Pulmonary Hypertension | — | P4 | CCC · 53 |
| Cirrhosis Of Liver | — | P4 | CCC · 52 |
| Idiopathic Pulmonary Fibrosis | — | P3 | CC · 45 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ambrisentan in Acute Kidney Injury. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ambrisentan-acute-kidney-injury
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