Anti-Il13Ralpha2 Car T-Cells
Astrocytoma, IDH-Mutant, Grade 4
Explore 12 assets in Astrocytoma, IDH-Mutant, Grade 4 →Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
City of Hope Medical Center
Modality
UNKNOWN
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07544992CT.gov Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Astrocytoma, IDH-Mutant, Grade 4
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Anti-Il13Ralpha2 Car T-Cells (this asset) | City of Hope Medical Center | P1 | CC · 43 |
| Safusidenib | Nuvation Bio Inc. | P3 | B |
| Nivolumab | Andrew P. Groves | P2 | B |
| gi-102 | Mayo Clinic | P2 | CCC |
| Ipilimumab | National Cancer Institute (NCI) | P2 | CCC |
| Pembrolizumab | Mayo Clinic | P2 | CCC |
| Ribociclib | St. Jude Children's Research Hospital | P1 | CC |
| Nivestim | St. Jude Children's Research Hospital | P1 | CC |
| Trametinib | St. Jude Children's Research Hospital | P1 | CC |
+7 more in the Astrocytoma, IDH-Mutant, Grade 4 cohort
Other indications for Anti-Il13Ralpha2 Car T-Cells
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| IDH-Wildtype Glioblastoma | — | P1 | CC · 43 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Anti-Il13Ralpha2 Car T-Cells in Astrocytoma, IDH-Mutant, Grade 4. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/anti-il13ralpha2-car-t-cells-astrocytoma-idh-mutant-grade-4
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →