Floatz Rating
BB66/100
Confidence
Indicative
Sponsor
Asian Institute Of Medical Sciences
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
62High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07461532CT.gov Efficacy of Apixaban in Treating Portal Vein Thrombosis Occurring More Than One Year After LSD | — | Recruiting | — | — | — |
NCT07521332CT.gov Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis | — | Recruiting | — | — | — |
NCT07461545CT.gov Efficacy of Apixaban in the Treatment of Portal Vein Thrombosis Occurring More Than One Year After LS | — | Recruiting | — | — | — |
NCT05869591CT.gov DOAC in Patients with Child a or B Liver Cirrhosis | — | Recruiting | — | — | — |
NCT07132515CT.gov Efficacy & Safety of Anticoagulants in Cirrhosis ± HCC | — | Recruiting | — | — | — |
NCT05304455CT.gov Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection | — | Completed | — | — | — |
NCT04874428CT.gov Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis | — | Recruiting | — | — | — |
NCT04645550CT.gov Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy（ESAWAAPT） | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Cirrhosis Of Liver
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Apixaban (this asset) | Asian Institute Of Medical Sciences | Approved | BB · 66 |
| Veruprevir | AbbVie | P3 | A |
| Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-Nh2 (4-9 Disulfide) | General Hospital of Shenyang Military Region | P4 | BBB |
| Tolvaptan | Institute of Liver and Biliary Sciences, India | P4 | BBB |
| Normal Human Serum Albumin | King George's Medical University | P4 | BBB |
| Cholyl-Lysl-Fluorescein | Norgine | P3 | BBB |
| Ribavirin | Peking University People's Hospital | P4 | BBB |
| Ombitasvir | AbbVie | P3 | BBB |
| Telbivudine | Lin Bingliang | P4 | BBB |
+42 more in the Cirrhosis Of Liver cohort
Other indications for Apixaban
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Venous Thromboembolism | — | P4 | BBB · 79 |
| Atrial Fibrillation | — | P4 | BBB · 77 |
| Transient Ischemic Attack | — | P4 | BBB · 73 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Apixaban in Cirrhosis Of Liver. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/apixaban-cirrhosis-of-liver
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