Arsenic Trioxide
Acute Myeloid Leukemia With Mutated NPM1
Explore 14 assets in Acute Myeloid Leukemia With Mutated NPM1 →Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
The University of Hong Kong
Modality
Small molecule
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04689815CT.gov Oral Arsenic Trioxide for NPM1-mutated AML | — | Unknown | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Myeloid Leukemia With Mutated NPM1
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Arsenic Trioxide (this asset) | The University of Hong Kong | P2 | CCC · 53 |
| Cytarabine | Shen yang | P3 | B |
| Azacitidine | Shen yang | P2 | B |
| Daunomycin | Shen yang | P2 | B |
| Venetoclax | Kura Oncology, Inc. | P2 | B |
| BN104 | Institut de Recherches Internationales Servier (I.R.I.S.) | P1/2 | CC |
| Revumenib | National Cancer Institute (NCI) | P1 | CC |
| Mezigdomide | Massachusetts General Hospital | P1 | CC |
| Quizartinib | Kura Oncology, Inc. | P1 | CC |
+6 more in the Acute Myeloid Leukemia With Mutated NPM1 cohort
Other indications for Arsenic Trioxide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Promyelocytic Leukemia | — | P4 | BBB · 79 |
| Plasma Cell Myeloma | — | P2 | BB · 71 |
| Central Nervous System Neoplasm | — | P2 | BB · 65 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Arsenic Trioxide in Acute Myeloid Leukemia With Mutated NPM1. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/arsenic-trioxide-acute-myeloid-leukemia-with-mutated-npm1
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