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Floatz Rating
CCC54/100
Confidence
Indicative
v0.2
Sponsor
Henan Cancer Hospital
Modality
UNKNOWN
Development Phase
Phase 2/3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
ARX788 in HER2-positive Metastatic Breast Cancer Patients
Not Yet Recruiting
A Study of ARX788 Combined With Pyrotinib Maleate Versus TCBHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients
Active Not Recruiting
ARX788 in HER2-positive Breast Cancer Patients With Brain Metastases
Unknown
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · HER2 Positive Breast Carcinoma

AssetSponsorPhaseRating
arx788 (this asset)Henan Cancer HospitalP2/3CCC · 54
TrastuzumabSWOG Cancer Research NetworkP4BB
PertuzumabSWOG Cancer Research NetworkP4BB
RibociclibDanish Breast Cancer Cooperative GroupP3BB
DocetaxelOhio State University Comprehensive Cancer CenterP3BB
CapecitabineMedSIRP4BB
Vinorelbine DitartrateFudan UniversityP3BB
CyclophosphamideNational University Hospital, SingaporeP3BB
EpirubicinOhio State University Comprehensive Cancer CenterP3BB

+42 more in the HER2 Positive Breast Carcinoma cohort

Other indications for arx788

IndicationSponsorPhaseRating
NeoplasmP2B · 60
AngiosarcomaP2CCC · 53
Hormone Receptor-Positive Breast CancerP2CCC · 53

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. arx788 in HER2 Positive Breast Carcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/arx788-her2-positive-breast-carcinoma

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