Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Boundless Bio, Inc.
Modality
UNKNOWN
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05827614CT.gov Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications | — | Terminated | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Cervical Squamous Cell Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Bbi-825 (this asset) | Boundless Bio, Inc. | P1 | CC · 43 |
| Cis-Diamminedichloroplatinum Ii | National Cancer Institute (NCI) | P2 | BB |
| Nivestim | National Cancer Institute (NCI) | P2 | B |
| Veliparib | National Cancer Institute (NCI) | P2 | B |
| Nogitecan | National Cancer Institute (NCI) | P2 | B |
| Rigosertib | Traws Pharma, Inc. | P2 | B |
| Pegfilgrastim | National Cancer Institute (NCI) | P2 | B |
| Cetuximab | Hummingbird Bioscience | P1/2 | CCC |
| Atezolizumab | M.D. Anderson Cancer Center | P2 | CCC |
+24 more in the Cervical Squamous Cell Carcinoma cohort
Other indications for Bbi-825
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Endometrial Carcinoma | — | P1 | CC · 43 |
| Head And Neck Squamous Cell Carcinoma | — | P1 | CC · 43 |
| Skin Squamous Cell Carcinoma | — | P1 | CC · 43 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Bbi-825 in Cervical Squamous Cell Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/bbi-825-cervical-squamous-cell-carcinoma
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