Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Dana-Farber Cancer Institute
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06677190CT.gov Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Vaginal Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Belzutifan (this asset) | Dana-Farber Cancer Institute | P2 | CCC · 53 |
| Fludarabine | Christian Hinrichs | P2 | BB |
| Cyclophosphamide | Christian Hinrichs | P2 | BB |
| L-Cysteinamide, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-N-(2-Hydroxy-1-(Hydroxymethyl)Propyl)-, Cyclic (2->7)-Disulfide, (R-(R*,R*))- | Alliance for Clinical Trials in Oncology | P3 | B |
| e7 tcr-t cells | Christian Hinrichs | P2 | B |
| Durvalumab | M.D. Anderson Cancer Center | P2 | B |
| Fondaparinux | Masonic Cancer Center, University of Minnesota | P2 | B |
| Young Til | National Cancer Institute (NCI) | P2 | B |
| Plasmid Encoded Il-12 | M.D. Anderson Cancer Center | P2 | CCC |
+19 more in the Vaginal Cancer cohort
Other indications for Belzutifan
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Renal Cell Carcinoma | — | P3 | BBB · 73 |
| Von Hippel-Lindau Disease | — | P3 | BB · 64 |
| Clear Cell Renal Carcinoma | — | P2 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- FludarabineChristian HinrichsBB
- CyclophosphamideChristian HinrichsBB
- L-Cysteinamide, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-N-(2-Hydroxy-1-(Hydroxymethyl)Propyl)-, Cyclic (2->7)-Disulfide, (R-(R*,R*))-Alliance for Clinical Trials in OncologyB
- e7 tcr-t cellsChristian HinrichsB
- DurvalumabM.D. Anderson Cancer CenterB
Citation
Floatz Terminal. Belzutifan in Vaginal Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/belzutifan-vaginal-cancer
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