Floatz Rating
CC40/100
Confidence
Indicative
Sponsor
Bellicum Pharmaceuticals
Modality
Cell therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02065869CT.gov Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant | — | Terminated | — | — | — |
NCT03301168CT.gov Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Lymphoblastic Leukemia
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Bpx-501 T Cells (this asset) | Bellicum Pharmaceuticals | P1/2 | CC · 40 |
| Peripheral Blood Stem Cells, Allogeneic, Cd34 Positive | Fred Hutchinson Cancer Center | P2/3 | BBB |
| Gm-Csf | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | P4 | BBB |
| Equine Atg | Instituto Nacional de Cancer, Brazil | P3 | BBB |
| Thioguanine Anhydrous | St. Jude Children's Research Hospital | P4 | BBB |
| Asparaginase | Centre Hospitalier Universitaire de Nice | P4 | BB |
| Daunomycin | PETHEMA Foundation | P4 | BB |
| Vincristine Sulfate | Children's Oncology Group | P3 | BB |
| Cyclophosphamide | Sawa Ito, MD | P4 | BB |
+42 more in the Acute Lymphoblastic Leukemia cohort
Other indications for Bpx-501 T Cells
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Childhood Acute Myeloid Leukemia | — | P1/2 | CC · 47 |
| Inborn Error Of Immunity | — | P1/2 | CC · 47 |
| Aplastic Anemia | — | P1/2 | CC · 47 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- Peripheral Blood Stem Cells, Allogeneic, Cd34 PositiveFred Hutchinson Cancer CenterBBB
- Gm-CsfXinhua Hospital, Shanghai Jiao Tong University School of MedicineBBB
- Equine AtgInstituto Nacional de Cancer, BrazilBBB
- Thioguanine AnhydrousSt. Jude Children's Research HospitalBBB
- AsparaginaseCentre Hospitalier Universitaire de NiceBB
Citation
Floatz Terminal. Bpx-501 T Cells in Acute Lymphoblastic Leukemia. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/bpx-501-t-cells-acute-lymphoblastic-leukemia
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