Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Brian Henick, MD
Modality
monoclonal_antibody
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06673329CT.gov Brodalumab in the Treatment of Immune-Related Adverse Events | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Lip And Oral Cavity Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Brodalumab (this asset) | Brian Henick, MD | P1 | CC · 43 |
| Nivolumab | National Cancer Institute (NCI) | P2 | B |
| Cis-Diamminedichloroplatinum Ii | Loren Mell, MD | P2 | B |
| Pembrolizumab | Loren Mell, MD | P2 | CCC |
| Anti-Her2 Antibody-Drug Conjugate A166 | Klus Pharma Inc. | P1/2 | CCC |
| (18F)FPPRGD2 | Sanjiv Sam Gambhir | P1/2 | CCC |
| Fludeoxyglucose | Sanjiv Sam Gambhir | P1/2 | CCC |
| Talaporfin | Light Sciences LLC | P1 | CC |
| Mogamulizumab | Osaka University | P1 | CC |
+13 more in the Lip And Oral Cavity Carcinoma cohort
Other indications for Brodalumab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Systemic Sclerosis | — | P1 | CC · 47 |
| Thyroid Cancer | — | P1 | CC · 41 |
| Female Reproductive Organ Cancer | — | P1 | CC · 41 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Brodalumab in Lip And Oral Cavity Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/brodalumab-lip-and-oral-cavity-carcinoma
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