Floatz Rating
CC46/100
Confidence
Indicative
Sponsor
Vanderbilt University
Modality
Small molecule
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02187445CT.gov Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Chest Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Budesonide (this asset) | Vanderbilt University | P1 | CC · 46 |
| Tocilizumab | Assistance Publique - Hôpitaux de Paris | P3 | BB |
| Tinzaparin | Assistance Publique - Hôpitaux de Paris | P3 | B |
| Atorvastatin | Dr. med. Mahir Karakas | P3 | B |
| Aspirin | Dr. med. Mahir Karakas | P3 | B |
| Defibrotide | New York Medical College | P2 | B |
| a-001 | Anthera Pharmaceuticals | P2 | B |
| Unfractionated Heparin | Craig Seaman | P2 | CCC |
| Azithromycin | University of Mississippi Medical Center | P1 | CC |
+2 more in the Acute Chest Syndrome cohort
Other indications for Budesonide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Asthma | — | P4 | BBB · 76 |
| Childhood Acute Lymphoblastic Leukemia | — | P4 | B · 58 |
| Primary Biliary Cholangitis | — | P3 | B · 58 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Budesonide in Acute Chest Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 13, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/budesonide-acute-chest-syndrome
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