Busulfanum
Adult Central Nervous System Germ Cell Tumor
Floatz Rating
CC47/100
Confidence
Indicative
Sponsor
City of Hope Medical Center
Modality
Small molecule
Development Phase
Phase 1
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
32Moderate confidence
Detailed axis rationale is planned and will be published soon.
No trial-level evidence is linked to this axis yet.
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Adult Central Nervous System Germ Cell Tumor
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Busulfanum (this asset) | City of Hope Medical Center | P1 | CC · 47 |
| Palbociclib | Abramson Cancer Center at Penn Medicine | P2 | CCC |
| Palifosfamide-Tris | Indiana University | P2 | CCC |
| Melphalan | City of Hope Medical Center | P1 | CC |
| Nogitecan | City of Hope Medical Center | P1 | CC |
| Nivestim | City of Hope Medical Center | P1 | CC |
| EF-5 | National Cancer Institute (NCI) | P1 | C |
Other indications for Busulfanum
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Myelodysplastic/Myeloproliferative Neoplasm | — | P2/3 | BBB · 74 |
| Graft Versus Host Disease | — | P4 | BBB · 72 |
| Disease Related To Hematopoietic Stem Cell Transplant | — | P3 | BBB · 72 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Busulfanum in Adult Central Nervous System Germ Cell Tumor. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/busulfanum-adult-central-nervous-system-germ-cell-tumor
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →