Busulfanum
X-Linked Lymphoproliferative Syndrome
Explore 10 assets in X-Linked Lymphoproliferative Syndrome →Floatz Rating
D30/100
Confidence
Indicative
Sponsor
Masonic Cancer Center, University of Minnesota
Modality
Small molecule
Development Phase
N/A
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01652092CT.gov Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · X-Linked Lymphoproliferative Syndrome
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Busulfanum (this asset) | Masonic Cancer Center, University of Minnesota | N/A | D · 30 |
| Thiotepa | University of Florida | P2 | BB |
| Cyclophosphamide | Masonic Cancer Center, University of Minnesota | P2 | B |
| Cytarabine | Baylor College of Medicine | P2 | B |
| Fludarabine | Washington University School of Medicine | P2 | CCC |
| Alemtuzumab | Washington University School of Medicine | P2 | CCC |
| Melphalan | Washington University School of Medicine | P2 | CCC |
| Campath-1H | Baylor College of Medicine | P2 | CCC |
| Icaspase9-Transduced T Cells | Baylor College of Medicine | P1 | CC |
+8 more in the X-Linked Lymphoproliferative Syndrome cohort
Other indications for Busulfanum
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Myelodysplastic/Myeloproliferative Neoplasm | — | P2/3 | BBB · 76 |
| Graft Versus Host Disease | — | P4 | BBB · 74 |
| Disease Related To Hematopoietic Stem Cell Transplant | — | P3 | BBB · 74 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Busulfanum in X-Linked Lymphoproliferative Syndrome. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/busulfanum-x-linked-lymphoproliferative-syndrome
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