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Carboplatin

Hormone Receptor-Positive Breast Cancer

Explore 112 assets in Hormone Receptor-Positive Breast Cancer
Floatz Rating
BB70/100
Confidence
Indicative
v0.2
Sponsor
Avenzo Therapeutics, Inc.
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
61High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Study of AVZO-021 in Patients With Advanced Solid Tumors
Recruiting
Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
Recruiting
(VELA) Study of BLU-222 in Advanced Solid Tumors
Terminated
Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD)
Active Not Recruiting
Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab With or Without Estrogen Deprivation in Treating Patients With Hormone Receptor-Positive, HER2-Positive Operable or Locally Advanced Breast Cancer
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Hormone Receptor-Positive Breast Cancer

AssetSponsorPhaseRating
Carboplatin (this asset)Avenzo Therapeutics, Inc.P3BB · 70
EverolimusEllipses PharmaP4BBB
ExemestaneFujian Cancer HospitalP4BBB
AnastrozoleUniversity of Illinois at ChicagoP4BBB
RibociclibBeOne MedicinesP4BBB
PalbociclibBeOne MedicinesP3BBB
CapecitabineKristina A. FanucciP4BBB
AbemaciclibBeOne MedicinesP4BBB
ElacestrantWest German Study GroupP3BB

+42 more in the Hormone Receptor-Positive Breast Cancer cohort

Other indications for Carboplatin

IndicationSponsorPhaseRating
Lung Large Cell CarcinomaP4A · 80
Primary Peritoneal CarcinomaP3BBB · 76
Non-Small Cell Squamous Lung CarcinomaP3BBB · 76

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Carboplatin in Hormone Receptor-Positive Breast Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/carboplatin-hormone-receptor-positive-breast-cancer

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