Floatz logo
Floatz Rating
BB64/100
Confidence
Indicative
v0.2
Sponsor
Bristol-Myers Squibb
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
64High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Not Yet Recruiting
Study of IBI3005 Combination Therapy in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors
Not Yet Recruiting
A Phase Ib/II Study of 7MW3711 Combined With JS207 in Advanced Solid Tumors
Recruiting
A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)
Recruiting
A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC
Recruiting
A Study of ASP3082 in Adults With Advanced Solid Tumors
Recruiting
(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations
Terminated
(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC
Terminated
Anlotinib Combined With Carboplatin/Paclitaxel as First-line Treatment in Patients With Advanced Ovarian Cancer
Active Not Recruiting
IBI188 Combination Therapy in Solid Tumors
Terminated
Show 64 more trials
Study of SAR444881 Administered Alone and in Combination With Other Therapeutics in Participants With Advanced Solid Tumors
Terminated
A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
Recruiting
A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)
Terminated
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411
Terminated
A Study of HB002.1T Plus Chemotherapy in Subjects With Solid Tumor
Unknown
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Active Not Recruiting
A Study of MK-0482 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-0482-001)
Completed
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
Active Not Recruiting
9-ING-41 in Patients With Advanced Cancers
Active Not Recruiting
A Study to Evaluate the Effects of Rifampin on Pharmacokinetics (PK) of Pevonedistat in Participants With Advanced Solid Tumors
Completed
Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)
Completed
A Study of Anti-VEGF Monoclonal Antibody hPV19 in Patients With Solid Tumors
Unknown
A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors
Active Not Recruiting
Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001)
Completed
A Study to Evaluate the Effects of Pevonedistat on the Corrected QT (QTc) Interval in Participants With Advanced Solid Tumors
Completed
Surgery With or Without Chemotherapy for Stage I NSCLC With Micropapillary Component ≥ 20%
Recruiting
A Study of SHR-1210 in Combination With Pemetrexed and Carboplatin in Subjects With Non-squamous NSCLC
Completed
A Study of [14 C]-Pevonedistat in Participants With Advanced Solid Tumors
Completed
A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)
Completed
Study of Vibostolimab Alone and in Combination With Pembrolizumab in Advanced Solid Tumors (MK-7684-001) ( KEYVIBE-001)
Completed
A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors
Terminated
Study of Epacadostat (INCB024360) Alone and In Combination With Pembrolizumab (MK-3475) With Chemotherapy and Pembrolizumab Without Chemotherapy in Participants With Advanced Solid Tumors (MK-3475-434)
Completed
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
Active Not Recruiting
Dose Escalation and Expansion Study of GSK3359609 in Participants With Selected Advanced Solid Tumors (INDUCE-1)
Completed
Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole
Terminated
First in Human Study of M4344 in Participants With Advanced Solid Tumors
Completed
Ph Ib/BGJ398/Cervix and Other Solid Tumors
Withdrawn
A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas
Completed
Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors
Completed
A Study Evaluating Veliparib as a Single Agent or in Combination With Chemotherapy in Subjects With Solid Tumors
Completed
A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors
Completed
Study to Evaluate GSK3052230 in Combination With Paclitaxel and Carboplatin, or Docetaxel or as Single Agent in Subjects With Solid Malignancies and Deregulated Fibroblast Growth Factor (FGF) Pathway Signaling
Completed
Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors
Completed
Study of Pembrolizumab (MK-3475) Monotherapy in Advanced Solid Tumors and Pembrolizumab Combination Therapy in Advanced Non-small Cell Lung Cancer/ Extensive-disease Small Cell Lung Cancer (MK-3475-011/KEYNOTE-011)
Completed
Debio 1143 in Combination With Carboplatin and Paclitaxel in Patient With Advanced Solid Malignancies
Terminated
A Study of Veliparib in Combination With Carboplatin and Paclitaxel in Japanese Subjects With Solid Tumors
Completed
Treatment Extension Study for Patients Who Have Previously Participated and Have Benefited From Iniparib in a Clinical Trial
Completed
Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors
Completed
ABT-888, Carboplatin, and Paclitaxel for Cancer With Liver or Kidney Problems
Withdrawn
BKM120 + Carboplatin + Paclitaxel for Patients With Advanced Solid Tumors
Completed
Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer
Terminated
A Study in Advanced Solid Tumors
Completed
A Phase I/II Study of Paclitaxel, Carboplatin and YM155 (Survivin Suppressor) in Subjects With Solid Tumors (Phase I) and Advanced Non-Small Cell Lung Carcinoma (Phase II)
Completed
ASA404 in Combination With Carboplatin/Paclitaxel/Cetuximab in Treating Patients With Refractory Solid Tumors
Withdrawn
Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Participants With Advanced Solid Tumors (P04722, MK-7454-004)
Terminated
A Study of R1507 in Combination With Multiple Standard Chemotherapy Treatments in Patients With Advanced Solid Tumors
Terminated
QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancer
Terminated
Phase I Study of TAS-106 in Combo With Carboplatin
Completed
A Safety and Efficacy Study of Carboplatin, Paclitaxel, Bevacizumab and CA4P in Non-Small Cell Lung Cancer
Completed
A Dose Escalation Study of Adavosertib (MK-1775) in Combination With Either Gemcitabine, Cisplatin, or Carboplatin in Adults With Advanced Solid Tumors (MK-1775-001)
Completed
LBH589, Paclitaxel, Carboplatin +/- Bevacizumab for Solid Tumors
Completed
Feasibility Study of Pazopanib in Combination With Chemotherapy in Gynaecological Tumors
Completed
Azacitidine and Valproic Acid Plus Carboplatin in Patients With Ovarian Cancer
Completed
Trial Exploring Afatinib (BIBW 2992) + Paclitaxel (Part A), Afatinib + Paclitaxel + Bevacizumab (Part B), Afatinib + Carboplatin (Part C) and Afatinib+ Paclitaxel +Carboplatin(Part D) in Patients With Advanced Solid Tumours
Completed
Phase I Study in Patients With Solid Tumours
Completed
A Study Evaluating BSI-201 in Combination With Chemotherapeutic Regimens in Subjects With Advanced Solid Tumors
Completed
Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC)
Completed
A Study of ADH 1 in Combination With Carboplatin, or Docetaxel or Capecitabine
Completed
A Study To Find The Best Dose Of SU011248 When Given With Pemetrexed, Pemetrexed And Cisplatin Or Pemetrexed And Carboplatin In Patients With Advanced Solid Tumors
Completed
Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor
Completed
Study Of SU011248 In Combination With Paclitaxel/Carboplatin In Patients With Advanced Solid Tumors
Completed
AMG 531 in Patients With Advanced Malignancy Receiving Treatment With Carboplatin
Completed
Safety and Effectiveness of Combretastatin A-4 Phosphate Combined With Chemotherapy in Advanced Solid Tumors
Completed
A Phase II Study of Carboplatin Plus Irinotecan Versus Irinotecan in Children With Refractory Solid Tumors
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Neoplasm

AssetSponsorPhaseRating
Carboplatin (this asset)Bristol-Myers SquibbP3BB · 64
PanitumumabAstellas Pharma IncP2BBB
Granulocyte Colony-Stimulating Factor LenograstimSanofiP4BB
DexmedetomidineMedical College of WisconsinP4BB
LidocaineMedical College of WisconsinP4BB
RelatlimabBristol-Myers SquibbP2BB
Vitamin DTanta UniversityP4BB
GlycopyrrolateMedical College of WisconsinP4BB
Dinitrogen MonoxideMedical College of WisconsinP4BB

+42 more in the Neoplasm cohort

Other indications for Carboplatin

IndicationSponsorPhaseRating
Lung Large Cell CarcinomaP4A · 80
Primary Peritoneal CarcinomaP3BBB · 76
Non-Small Cell Squamous Lung CarcinomaP3BBB · 76

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Carboplatin in Neoplasm. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/carboplatin-neoplasm

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