Floatz logo
Floatz Rating
B58/100
Confidence
Indicative
v0.2
Sponsor
Alliance for Clinical Trials in Oncology
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
58High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
Recruiting
LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer
Active Not Recruiting
Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study
Recruiting
Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC)
Recruiting
Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer
Active Not Recruiting
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
Active Not Recruiting
Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer
Enrolling By Invitation
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
Terminated
M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
Active Not Recruiting
Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate
Active Not Recruiting
Show 17 more trials
Prostate Cancer Biomarker Enrichment and Treatment Selection
Active Not Recruiting
Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy
Completed
Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC
Completed
Prostate Cancer Intensive, Non-Cross Reactive Therapy (PRINT) for Castration Resistant Prostate Cancer (CRPC)
Completed
Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
Terminated
A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors
Completed
Tivantinib in Treating Patients With Metastatic Prostate Cancer
Completed
A Phase I/II Study of TRC105 in Metastatic Castrate Resistant Prostate Cancer (CRPC)
Completed
Carboplatin, Everolimus, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Progressed After Docetaxel
Completed
Ridaforolimus (AP23573/MK-8669) in Participants With Taxane-Resistant Androgen-Independent Prostate Cancer (AIPC)(MK-8669-017)
Completed
Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer
Completed
Weekly Paclitaxel, Low-Dose Estramustine, and Carboplatin in the Treatment of Hormone Refractory Prostate Carcinoma
Completed
Combination Chemotherapy Plus Filgrastim in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Hormone Therapy
Completed
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu
Completed
Estramustine, Docetaxel, and Carboplatin in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
Completed
Flavopiridol Plus Cisplatin or Carboplatin in Treating Patients With Advanced Solid Tumors
Completed
Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Prostate Cancer

AssetSponsorPhaseRating
Carboplatin (this asset)Alliance for Clinical Trials in OncologyP3B · 58
AvodartBay State Clinical Trials, Inc.P4BBB
DesfluranePeter MacCallum Cancer Centre, AustraliaP4BBB
PropofolPeter MacCallum Cancer Centre, AustraliaP4BBB
DegarelixBayerP4BBB
Flotufolastat F 18Washington University School of MedicineP4BB
AVOLVEMasonic Cancer Center, University of MinnesotaP4BB
EstramustineThe University of Texas Health Science Center, HoustonP3BB
PasireotideRECORDATI GROUPP4BB

+42 more in the Prostate Cancer cohort

Other indications for Carboplatin

IndicationSponsorPhaseRating
Lung Large Cell CarcinomaP4A · 80
Primary Peritoneal CarcinomaP3BBB · 76
Non-Small Cell Squamous Lung CarcinomaP3BBB · 76

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Carboplatin in Prostate Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/carboplatin-prostate-cancer

Need depth?

Order a full diligence report on this asset.

Order report →

Are you the sponsor?

Submit your data room for a Verified Rating. The public-data rating remains visible alongside.

Contact →