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Cediranib

Metastatic Prostate Carcinoma

Explore 229 assets in Metastatic Prostate Carcinoma
Floatz Rating
BB65/100
Confidence
Indicative
v0.2
Sponsor
National Cancer Institute (NCI)
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
50High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery
Completed
Testing Two Oral Drugs Combination (Cediranib and Olaparib) Compared to a Single Drug (Olaparib) for Men With Advanced Prostate Cancer
Active Not Recruiting
Niclosamide and Enzalutamide in Treating Patients With Castration-Resistant, Metastatic Prostate Cancer
Completed
Enzalutamide With Ribociclib in Treating Patients With Metastatic Castrate-Resistant, Chemotherapy Naive Prostate Cancer That Retains Retinoblastoma Expression
Terminated
Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer
Active Not Recruiting
Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Metastatic Prostate Carcinoma

AssetSponsorPhaseRating
Cediranib (this asset)National Cancer Institute (NCI)P2BB · 65
AXUMINVA Greater Los Angeles Healthcare SystemP4BBB
LeuporelinMayo ClinicP4BBB
AbirateroneMayo ClinicP4BB
PrednisoneMayo ClinicP4BB
PembrolizumabCuraCell TX ABP2BB
CabazitaxelAstraZenecaP4BB
Sipuleucel-TYale UniversityP2BB
DegarelixPraful Ravi, MB BCHir, MRCPP3BB

+42 more in the Metastatic Prostate Carcinoma cohort

Other indications for Cediranib

IndicationSponsorPhaseRating
GliosarcomaP2BBB · 76
Metastatic MelanomaP2BBB · 73
Adult GlioblastomaP2BBB · 73

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Cediranib in Metastatic Prostate Carcinoma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/cediranib-metastatic-prostate-carcinoma

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