Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Institute of Cancer Research, United Kingdom
Modality
UNKNOWN
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04065269CT.gov ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no Loss | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Female Reproductive Organ Cancer
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Ceralasertib (this asset) | Institute of Cancer Research, United Kingdom | P2 | CCC · 53 |
| Adriamycin | AstraZeneca | P2 | BB |
| Carboplatin | AbbVie | P2/3 | BB |
| Indocyanine Green | Istanbul University | P4 | BB |
| Nivolumab | Clovis Oncology, Inc. | P2 | B |
| Ipilimumab | M.D. Anderson Cancer Center | P2 | B |
| Atezolizumab | M.D. Anderson Cancer Center | P2 | B |
| Normal Human Serum Albumin | Joachim Zdolsek | P4 | B |
| Ringer'S Acetate | Joachim Zdolsek | P4 | B |
+42 more in the Female Reproductive Organ Cancer cohort
Other indications for Ceralasertib
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Non-Small Cell Lung Carcinoma | — | P3 | BB · 69 |
| Breast Carcinoma | — | P2 | B · 60 |
| Breast Cancer | — | P2 | B · 60 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Ceralasertib in Female Reproductive Organ Cancer. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/ceralasertib-female-reproductive-organ-cancer
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