Cetuximab
Diffuse Midline Glioma, H3 K27-Altered
Explore 8 assets in Diffuse Midline Glioma, H3 K27-Altered →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
University of Miami
Modality
monoclonal_antibody
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT05956821CT.gov Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Diffuse Midline Glioma, H3 K27-Altered
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cetuximab (this asset) | University of Miami | P1/2 | CCC · 48 |
| Valproic Acid | University of Göttingen | P3 | B |
| Cbl-0137 Free Base | Children's Oncology Group | P1/2 | CC |
| Vipivotide Tetraxetan | Memorial Sloan Kettering Cancer Center | P1 | CC |
| Atezolizumab | German Cancer Research Center | P1 | CC |
| h3k27m peptide vaccine | German Cancer Research Center | P1 | CC |
| Imiquimod | German Cancer Research Center | P1 | CC |
| Lorlatinib | Nationwide Children's Hospital | Early P1 | C |
| azd1390 | Children's Oncology Group | P1 | NR |
Other indications for Cetuximab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Colon Adenocarcinoma | — | P3 | BB · 70 |
| Rectal Carcinoma | — | P2 | BB · 69 |
| Non-Small Cell Lung Carcinoma | — | P3 | BB · 69 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Cetuximab in Diffuse Midline Glioma, H3 K27-Altered. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cetuximab-diffuse-midline-glioma-h3-k27-altered
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