Floatz Rating
BB65/100
Confidence
Indicative
Sponsor
Yuhan Corporation
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
50Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06041529CT.gov Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension | — | Active Not Recruiting | — | — | — |
NCT06282549CT.gov Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients with Essential Hypertension | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Essential Hypertension
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Chlorthalidone (this asset) | Yuhan Corporation | Approved | BB · 65 |
| Hydrochlorothiazide | Yuhan Corporation | P4 | BBB |
| Amlodipine | Yuhan Corporation | P4 | BBB |
| Phentermine | VIVUS LLC | P4 | BB |
| Valsartan | ARKAY Therapeutics | P4 | BB |
| Labetalol | ProMedica Health System | P3 | BB |
| Dapagliflozin | University of Campinas, Brazil | P4 | BB |
| vi-0521 | VIVUS LLC | P4 | BB |
| Tomato Fruit Extract | Beata Krasinska | P4 | BB |
+35 more in the Essential Hypertension cohort
Other indications for Chlorthalidone
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Hypertensive Disorder | — | P4 | BB · 65 |
| Obesity Disorder | — | P4 | BB · 65 |
| Abdominal Obesity-Metabolic Syndrome | — | P4 | B · 62 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Chlorthalidone in Essential Hypertension. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/chlorthalidone-essential-hypertension
Are you the sponsor?
Submit your data room for a Verified Rating. The public-data rating remains visible alongside.
Contact →