Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Chimeric Therapeutics
Modality
Cell therapy
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT06055439CT.gov A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
73Indicative
Detailed axis rationale is planned and will be published soon.
Same indication · Neuroendocrine Neoplasm
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Chm-2101 Car-T Cells (this asset) | Chimeric Therapeutics | P1/2 | CC · 43 |
| Irinotecan | First Affiliated Hospital Xi'an Jiaotong University | P4 | BB |
| Fluorouracilum | ITM Solucin GmbH | P3 | BB |
| Cabozantinib | Fox Chase Cancer Center | P3 | BB |
| Everolimus | Exelixis | P3 | BB |
| Oxodotreotide | Fundación de investigación HM | P3 | BB |
| Surufatinib | Shanghai Changzheng Hospital | P3 | BB |
| L-Cysteinamide, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-N-(2-Hydroxy-1-(Hydroxymethyl)Propyl)-, Cyclic (2->7)-Disulfide, (R-(R*,R*))- | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | P4 | B |
| Carboplatin | First Affiliated Hospital Xi'an Jiaotong University | P4 | B |
+42 more in the Neuroendocrine Neoplasm cohort
Other indications for Chm-2101 Car-T Cells
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Gastric Cancer | — | P1/2 | CC · 41 |
| Colorectal Cancer | — | P1/2 | CC · 40 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Chm-2101 Car-T Cells in Neuroendocrine Neoplasm. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/chm-2101-car-t-cells-neuroendocrine-neoplasm
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