Floatz Rating
CCC53/100
Confidence
Indicative
Sponsor
Hospital General Universitario Gregorio Marañon
Modality
UNKNOWN
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
38Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07229040CT.gov A Double-blind Non Inferiority Clinical Trial to Compare the Nephroprotection of Cilastatn Versus Thiosulfate in Patients Undergoing Debulking Surgery With Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Cisplatin. | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
81High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Kidney Injury
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cilastatine (this asset) | Hospital General Universitario Gregorio Marañon | P2 | CCC · 53 |
| Angiotensin Ii | The Cleveland Clinic | P4 | BB |
| Everolimus | MARIO ABBUD FILHO | P4 | B |
| Gabapentin | Tanta University | P4 | B |
| Normal Human Serum Albumin | Institute of Liver and Biliary Sciences, India | P3 | B |
| Noradrenaline | University of California, Los Angeles | P4 | B |
| Apsolol | Taipei Veterans General Hospital, Taiwan | P4 | B |
| Dextran 40 For Injection | Ramathibodi Hospital | P2/3 | B |
| Conestat Alfa | University Hospital, Basel, Switzerland | P2 | B |
+22 more in the Acute Kidney Injury cohort
Other indications for Cilastatine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Ovarian Cancer | — | P2 | CCC · 53 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Cilastatine in Acute Kidney Injury. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cilastatine-acute-kidney-injury
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