Floatz Rating
B61/100
Confidence
Indicative
Sponsor
Ohio State University Comprehensive Cancer Center
Modality
Small molecule
Development Phase
Phase 2/3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
46Moderate confidence
Detailed axis rationale is planned and will be published soon.
No trial-level evidence is linked to this axis yet.
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Breast Carcinoma In Situ
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cimetidine (this asset) | Ohio State University Comprehensive Cancer Center | P2/3 | B · 61 |
| Letrozole | Alliance for Clinical Trials in Oncology | P4 | BBB |
| Exemestane | Alliance for Clinical Trials in Oncology | P4 | BBB |
| Tamoxifen | Alliance for Clinical Trials in Oncology | P4 | BB |
| Anastrozole | Alliance for Clinical Trials in Oncology | P4 | BB |
| Revaree Plus | Memorial Sloan Kettering Cancer Center | P4 | BB |
| Cyclophosphamide | Roswell Park Cancer Institute | P3 | BB |
| Toremifene | Fred Hutchinson Cancer Center | P4 | BB |
| Famotidine | Ohio State University Comprehensive Cancer Center | P2/3 | B |
+20 more in the Breast Carcinoma In Situ cohort
Other indications for Cimetidine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Breast Carcinoma | — | P2/3 | B · 61 |
| Breast Cancer | — | P2/3 | B · 60 |
| Cutaneous Melanoma | — | P2 | B · 57 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Cimetidine in Breast Carcinoma In Situ. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cimetidine-breast-carcinoma-in-situ
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