Cis-Diamminedichloroplatinum Ii
Malignant Peritoneal Mesothelioma
Explore 4 assets in Malignant Peritoneal Mesothelioma →Floatz Rating
CCC48/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
Small molecule
Development Phase
Phase 1/2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
33Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT02535312CT.gov Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin | — | Active Not Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Malignant Peritoneal Mesothelioma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cis-Diamminedichloroplatinum Ii (this asset) | National Cancer Institute (NCI) | P1/2 | CCC · 48 |
| Atezolizumab | M.D. Anderson Cancer Center | P2 | CCC |
| Celecoxib | David Bartlett | P1/2 | CCC |
| Interferon Alfa-2B | David Bartlett | P1/2 | CCC |
| Methoxyamine | National Cancer Institute (NCI) | P1/2 | CCC |
| Immunoglobulin G1, Anti-(Human Mesothelin) (Human Monoclonal Mf-T-Igg1 Heavy Chain), Disulfide With Human Monoclonal Mf-T-Igg1 .Lambda.-Chain, Dimer, N6-(4-((4-(3-(Bis(2-(((1,2-Dihydro-3-(Hydroxy-.Kappa.O)-1-Methyl-2-(Oxo-.Kappa.O)-4-Pyridinyl)Carbonyl)Amino)Ethyl)Amino)-2-((Bis(2-(((1,2-Dihydro-3-(Hydroxy-.Kappa.O)-1-Methyl-2-(Oxo-.Kappa.O)-4-Pyridinyl)Carbonyl)Amino)Ethyl)Amino)Methyl)Propyl)Phenyl)Amino)-1,4-Dioxobutyl)-L-Lysine Complex With Thorium-227Th | Bayer | P1 | CC |
| Rintatolimod | David Bartlett | P1/2 | CC |
| Pegargiminase | Polaris Group | P1 | CC |
| ct-95 | Context Therapeutics Inc. | P1 | CC |
Other indications for Cis-Diamminedichloroplatinum Ii
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Squamous Cell Lung Carcinoma | — | P4 | BBB · 78 |
| Primary Peritoneal Carcinoma | — | P3 | BBB · 77 |
| Adenocarcinoma | — | P4 | BBB · 76 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- AtezolizumabM.D. Anderson Cancer CenterCCC
- CelecoxibDavid BartlettCCC
- Interferon Alfa-2BDavid BartlettCCC
- MethoxyamineNational Cancer Institute (NCI)CCC
- Immunoglobulin G1, Anti-(Human Mesothelin) (Human Monoclonal Mf-T-Igg1 Heavy Chain), Disulfide With Human Monoclonal Mf-T-Igg1 .Lambda.-Chain, Dimer, N6-(4-((4-(3-(Bis(2-(((1,2-Dihydro-3-(Hydroxy-.Kappa.O)-1-Methyl-2-(Oxo-.Kappa.O)-4-Pyridinyl)Carbonyl)Amino)Ethyl)Amino)-2-((Bis(2-(((1,2-Dihydro-3-(Hydroxy-.Kappa.O)-1-Methyl-2-(Oxo-.Kappa.O)-4-Pyridinyl)Carbonyl)Amino)Ethyl)Amino)Methyl)Propyl)Phenyl)Amino)-1,4-Dioxobutyl)-L-Lysine Complex With Thorium-227ThBayerCC
Citation
Floatz Terminal. Cis-Diamminedichloroplatinum Ii in Malignant Peritoneal Mesothelioma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cis-diamminedichloroplatinum-ii-malignant-peritoneal-mesothelioma
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