Floatz Rating
B62/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
monoclonal_antibody
Development Phase
Phase 2
Status
Dormant
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
47High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01614795CT.gov Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma | — | Completed | — | — | — |
NCT00831844CT.gov Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Osteosarcoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cixutumumab (this asset) | National Cancer Institute (NCI) | P2 | B · 62 |
| Ipilimumab | Children's National Research Institute | P2 | BB |
| (+)-Vincristine | Milton S. Hershey Medical Center | P2 | BB |
| Olaparib | Fundación de investigación HM | P2 | BB |
| Etoposide | Eisai Limited | P2 | B |
| Irinotecan | Milton S. Hershey Medical Center | P2 | B |
| Cyclophosphamide | M.D. Anderson Cancer Center | P2 | B |
| Oxaliplatin | National Cancer Institute (NCI) | P2 | B |
| Nivolumab | Instituto do Cancer do Estado de São Paulo | P2 | B |
+42 more in the Osteosarcoma cohort
Other indications for Cixutumumab
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Non-Small Cell Lung Carcinoma | — | P2 | BB · 71 |
| Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | — | P2 | BB · 69 |
| Prostate Carcinoma | — | P2 | BB · 67 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Cixutumumab in Osteosarcoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cixutumumab-osteosarcoma
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