Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
University of Kansas Medical Center
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04934228CT.gov Mitigating the Pro-inflammatory Phenotype of Obesity | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Essential Hypertension
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Clonidine (this asset) | University of Kansas Medical Center | P1 | CC · 43 |
| Hydrochlorothiazide | Yuhan Corporation | P4 | BBB |
| Amlodipine | Yuhan Corporation | P4 | BBB |
| Labetalol | ProMedica Health System | P3 | BB |
| Glibenclamide | University of Campinas, Brazil | P4 | BB |
| Phentermine | VIVUS LLC | P4 | BB |
| Tomato Fruit Extract | Beata Krasinska | P4 | BB |
| vi-0521 | VIVUS LLC | P4 | BB |
| Dapagliflozin | University of Campinas, Brazil | P4 | BB |
+35 more in the Essential Hypertension cohort
Other indications for Clonidine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Delirium | — | P4 | BB · 65 |
| Catatonia | — | P4 | BB · 65 |
| Breast Neoplasm | — | P3 | B · 62 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Clonidine in Essential Hypertension. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/clonidine-essential-hypertension
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