Clopidogrel
Ischemic Stroke
Floatz Rating
BB71/100
Confidence
Indicative
Sponsor
Nanfang Hospital, Southern Medical University
Modality
Small molecule
Development Phase
Phase 4 / Approved
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
75High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07604298CT.gov Efficacy and Safety of Indobufen, Aspirin, Cilostazol and Clopidogrel in the Treatment of Ischemic Stroke | — | Not Yet Recruiting | — | — | — |
NCT07519889CT.gov Observational Study to Assess the Safety of rhTNK-tPA (Mingfule®) vs. Rt-PA (Actilyse®) in Treating Acute Ischemic Stroke | — | Not Yet Recruiting | — | — | — |
NCT07454707CT.gov Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial | — | Not Yet Recruiting | — | — | — |
NCT07347626CT.gov Eptifibatide for Extended Window Ischemic Stroke After Thrombolysis | — | Not Yet Recruiting | — | — | — |
NCT07335107CT.gov Intravenous Tirofiban After Bridging Therapy for Acute Stroke With Atherosclerotic Large Artery Occlusion | — | Not Yet Recruiting | — | — | — |
NCT07237308CT.gov BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis | — | Not Yet Recruiting | — | — | — |
NCT07275749CT.gov Acetyl-leucine in Post-stroke Ataxia | — | Recruiting | — | — | — |
NCT07201688CT.gov Phase III Clinical Trial of rhTNK-tPA in Treating Acute Ischemic Stroke With Extended Time Window. | — | Recruiting | — | — | — |
NCT06414499CT.gov Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅳ | — | Recruiting | — | — | — |
NCT06853535CT.gov Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE | — | Recruiting | — | — | — |
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NCT06601127CT.gov Study of Tiprogrel in the Treatment of High-risk Patients with Acute Ischemic Cerebrovascular Events (THRIVE). | — | Recruiting | — | — | — |
NCT06712004CT.gov A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke | — | Recruiting | — | — | — |
NCT06715007CT.gov Antiplatelet Therapy and Endothelial-stabilizing Agents in Cerebral Small Vessel Diseases | — | Recruiting | — | — | — |
NCT06587347CT.gov Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke | — | Not Yet Recruiting | — | — | — |
NCT06584812CT.gov Study to Assess Pharmacokinetics, Pharmacodynamics and Safety of Tiprogrel in Healthy Subjects | — | Completed | — | — | — |
NCT06591338CT.gov Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT06243133CT.gov Pair Antiplatelet THerapy in Ischemic Stroke With Intracranial Artery Stenosis | — | Not Yet Recruiting | — | — | — |
NCT05604638CT.gov Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke | — | Recruiting | — | — | — |
NCT05700266CT.gov Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis | — | Unknown | — | — | — |
NCT06053021CT.gov Antiplatelet Therapy for AIS Patients With Thrombocytopenia | — | Unknown | — | — | — |
NCT05387954CT.gov PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years | — | Recruiting | — | — | — |
NCT05752916CT.gov Intravenous Thrombolysis With rhTNK-tPA for Acute Non-large Vessel Occlusion in Extended Time Window | — | Completed | — | — | — |
NCT04818944CT.gov Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke | — | Withdrawn | — | — | — |
NCT06242145CT.gov Clopidogrel Versus Cilostazol in Large-vessel Ischemic Stroke | — | Completed | — | — | — |
NCT06269432CT.gov Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Ischemic STROKE（PATH-STROKE） | — | Completed | — | — | — |
NCT05445895CT.gov A Study to Evaluate the Efficacy and Safety of Renexin CR in Patients With Acute Non-cardioembolic Ischemic Stroke | — | Completed | — | — | — |
NCT05553613CT.gov Ticagrelor Versus Clopidogrel in Ischemic Stroke | — | Completed | — | — | — |
NCT05193071CT.gov Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST) | — | Completed | — | — | — |
NCT06242132CT.gov Clopidogrel Versus Cilostazol in Ischemic Stroke | — | Completed | — | — | — |
NCT04733742CT.gov Endovascular Treatment With Versus Without Intravenous rhTNK-tPA in Stroke | — | Completed | — | — | — |
NCT06591312CT.gov Combining Aspirin With Ticagrelor or Clopidogrel in Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT06591351CT.gov Combining Aspirin With Cilostazol or Clopidogrel in Large-vessel Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT06591299CT.gov Combining Aspirin With Cilostazol or Clopidogrel in Minor Stroke or TIA | — | Recruiting | — | — | — |
NCT04588337CT.gov INtravenous TNK for Acute isChemicsTroke in China | — | Completed | — | — | — |
NCT06120725CT.gov Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke | — | Completed | — | — | — |
NCT04738097CT.gov Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke | — | Completed | — | — | — |
NCT04797013CT.gov Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅱ | — | Completed | — | — | — |
NCT04809818CT.gov A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects | — | Completed | — | — | — |
NCT04847752CT.gov Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis | — | Recruiting | — | — | — |
NCT05476081CT.gov A REAl-life Study on Short-term DAPT in Patients With Ischemic Stroke or TIA | — | Completed | — | — | — |
NCT03961334CT.gov MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention | — | Unknown | — | — | — |
NCT04142151CT.gov Double Randomized and Placebo Controlled Trail of Sanchitongshu Combined Antiplatelet Drug to Prevent Ischemic Stroke | — | Unknown | — | — | — |
NCT06522113CT.gov Cilostazol and Aspirin in Stroke and TIA | — | Completed | — | — | — |
NCT03766581CT.gov A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel | — | Completed | — | — | — |
NCT03649711CT.gov Chronic Kidney Disease (CKD) Platelet Study | — | Completed | — | — | — |
NCT03552354CT.gov Argatroban Combined With Antiplatelet Versus Antiplatelet for Acute Ischemic Stroke | — | Completed | — | — | — |
NCT02983214CT.gov Diabetic Artery Obstruction: is it Possible to Reduce Ischemic Events With Cilostazol? | — | Completed | — | — | — |
NCT03431909CT.gov Evaluation Of HUK in Acute Stroke Patients: MRS and CTP | — | Completed | — | — | — |
NCT01924325CT.gov Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events | — | Unknown | — | — | — |
NCT01790997CT.gov Efficacy of DLBS1033 in Patients With Acute Ischemic Stroke | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
65High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Ischemic Stroke
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Clopidogrel (this asset) | Nanfang Hospital, Southern Medical University | Approved | BB · 71 |
| Ticagrelor | Sichuan Provincial People's Hospital | P4 | BBB |
| Cilostazol | Stanford University | P4 | BBB |
| Compound Edaravone | Nanfang Hospital, Southern Medical University | P4 | BBB |
| Argatroban | Second Affiliated Hospital, School of Medicine, Zhejiang University | P4 | BBB |
| 3-N-BUTYLPHTHALIDE | Nanfang Hospital, Southern Medical University | P4 | BBB |
| Tenecteplase | Hackensack Meridian Health | P4 | BBB |
| Aspirin | Nanfang Hospital, Southern Medical University | P4 | BB |
| Prednisolone | University of California, San Francisco | P4 | BB |
+42 more in the Ischemic Stroke cohort
Other indications for Clopidogrel
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Myocardial Infarction | — | P4 | A · 81 |
| Peripheral Arterial Disease | — | P4 | BBB · 77 |
| Transient Ischemic Attack | — | P4 | BBB · 77 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Citation
Floatz Terminal. Clopidogrel in Ischemic Stroke. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 13, 2026. https://terminal.floatz.ai/assets/clopidogrel-ischemic-stroke
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