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Floatz Rating
D30/100
Confidence
Indicative
v0.2
Sponsor
Institute of Hematology & Blood Diseases Hospital, China
Modality
UNKNOWN
Development Phase
N/A
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
15Indicative
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
BCMA/CD3 BsAb in the Treatment of High-risk Smoldering Multiple Myeloma
Not Yet Recruiting

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Smoldering Plasma Cell Myeloma

AssetSponsorPhaseRating
CM336 (this asset)Institute of Hematology & Blood Diseases Hospital, ChinaN/AD · 30
DexasoneRegeneron PharmaceuticalsP3BB
NivestimRegeneron PharmaceuticalsP3BB
LenalidomideIrene Ghobrial, MDP3BB
LinvoseltamabRegeneron PharmaceuticalsP3BB
DaratumumabRegeneron PharmaceuticalsP3BB
CyclophosphamideDana-Farber Cancer InstituteP2B
MelphalanPETHEMA FoundationP3B
BortezomibOmar Nadeem, MDP2B

+39 more in the Smoldering Plasma Cell Myeloma cohort

Other indications for CM336

IndicationSponsorPhaseRating
Plasma Cell MyelomaP3B · 63
Plasma Cell LeukemiaP2CCC · 53

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. CM336 in Smoldering Plasma Cell Myeloma. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026.
Accessed July 14, 2026.
https://terminal.floatz.ai/assets/cm336-smoldering-plasma-cell-myeloma

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