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Floatz Rating
BB65/100
Confidence
Indicative
v0.2Rating updated July 14, 2026
Sponsor
Novartis Pharmaceuticals
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2

Clinical Evidence

Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
67High confidence
Detailed axis rationale is planned and will be published soon.
TrialPhaseStatusNPrimary endpointReadout
A Trial of CTT1403 for Metastatic Castration Resistant Prostate Cancer
Completed
A Phase 1 Trial for Evaluation of the Safety, Pharmacokinetics, and [18F] Radiation Dosimetry of CTT1057
Completed

Competitive Position

Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
59High confidence
Detailed axis rationale is planned and will be published soon.

Same indication · Prostate Cancer

AssetSponsorPhaseRating
Ctt-1057 (this asset)Novartis PharmaceuticalsP3BB · 65
Flotufolastat F 18Washington University School of MedicineP4BBB
AVOLVEMasonic Cancer Center, University of MinnesotaP4BBB
DegarelixBayerP4BBB
EstramustineThe University of Texas Health Science Center, HoustonP3BBB
AvodartBay State Clinical Trials, Inc.P4BB
GoserelinBayerP4BB
PrednisoneMayo ClinicP4BB
FlutamideVA Office of Research and DevelopmentP4BB

+42 more in the Prostate Cancer cohort

Other indications for Ctt-1057

IndicationSponsorPhaseRating
Prostate NeoplasmP3BB · 64
Renal Cell CarcinomaP1CC · 40

Scientific Foundation

Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR

Planned for methodology v0.2.

Development Feasibility

How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR

Planned for methodology v0.2.

Commercial Opportunity

Commercial prize: addressable population, unmet need, and the value case for the indication.
NR

Planned for methodology v0.2.

IP & Exclusivity

Exclusivity position, covering patent protection and freedom-to-operate runway.
NR

Planned for methodology v0.2.

Manufacturing & Supply

Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR

Planned for methodology v0.2.

Related assets

Citation

Floatz Terminal. Ctt-1057 in Prostate Cancer. Methodology v0.2.
Rated under v0.2 effective July 8, 2026. Last refreshed July 14, 2026.
Accessed July 15, 2026.
https://terminal.floatz.ai/assets/ctt-1057-prostate-cancer

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