Cyclophosphamide
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Explore 16 assets in Chronic Inflammatory Demyelinating Polyradiculoneuropathy →Floatz Rating
CCC50/100
Confidence
Indicative
Sponsor
Kite, A Gilead Company
Modality
Small molecule
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
35Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07304154CT.gov A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases | — | Recruiting | — | — | — |
NCT07526493CT.gov Safety and Pharmacodynamics of QH103 Cell Injection in the Treatment of Patients With Relapsed/Refractory Antibody-Mediated Neurological Autoimmune Diseases. | — | Recruiting | — | — | — |
NCT04561557CT.gov Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Chronic Inflammatory Demyelinating Polyradiculoneuropathy
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cyclophosphamide (this asset) | Kite, A Gilead Company | P1 | CCC · 50 |
| Amifampridine | National Center for Research Resources (NCRR) | P3 | BB |
| Human Immunoglobulins | National Center for Research Resources (NCRR) | P3 | BB |
| i10e | Laboratoire français de Fractionnement et de Biotechnologies | P3 | B |
| Melphalan | Fred Hutchinson Cancer Center | P2 | CCC |
| Anti-Human T-Lymphocyte Immunoglobulin, Rabbit | Fred Hutchinson Cancer Center | P2 | CCC |
| Cytarabine | Fred Hutchinson Cancer Center | P2 | CCC |
| Prednisone | Fred Hutchinson Cancer Center | P2 | CCC |
| Camustine | Fred Hutchinson Cancer Center | P2 | CCC |
+10 more in the Chronic Inflammatory Demyelinating Polyradiculoneuropathy cohort
Other indications for Cyclophosphamide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Adult Acute Lymphoblastic Leukemia | — | P4 | BBB · 79 |
| Mycosis Fungoides | — | P4 | BBB · 78 |
| B-Cell Childhood Acute Lymphoblastic Leukemia | — | P3 | BBB · 78 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- AmifampridineNational Center for Research Resources (NCRR)BB
- Human ImmunoglobulinsNational Center for Research Resources (NCRR)BB
- i10eLaboratoire français de Fractionnement et de BiotechnologiesB
- MelphalanFred Hutchinson Cancer CenterCCC
- Anti-Human T-Lymphocyte Immunoglobulin, RabbitFred Hutchinson Cancer CenterCCC
Citation
Floatz Terminal. Cyclophosphamide in Chronic Inflammatory Demyelinating Polyradiculoneuropathy. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cyclophosphamide-chronic-inflammatory-demyelinating-polyradiculoneuropathy
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