Cyclophosphamide
Metastatic Malignant Neoplasm In The Lymph Nodes
Explore 16 assets in Metastatic Malignant Neoplasm In The Lymph Nodes →Floatz Rating
BB66/100
Confidence
Indicative
Sponsor
Laura M. Spring, MD
Modality
Small molecule
Development Phase
Phase 3
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
52Moderate confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT04443348CT.gov Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD) | — | Active Not Recruiting | — | — | — |
NCT00590785CT.gov Phase III Comparison of Adjuvant Chemotherapy W/High-Dose Cyclophosphamide Plus Doxorubicin (AC) vs Sequential Doxorubicin Fol by Cyclophosphamide (A-C) in High Risk Breast Cancer Patients With 0-3 Positive Nodes (Intergroup, CALGB 9394) | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Metastatic Malignant Neoplasm In The Lymph Nodes
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cyclophosphamide (this asset) | Laura M. Spring, MD | P3 | BB · 66 |
| Adriamycin | Laura M. Spring, MD | P3 | BB |
| Indocyanine Green | Isabelle Henskens | P4 | BB |
| Tamoxifen | National Cancer Institute (NCI) | P3 | BB |
| Ciprofloxacin | National Cancer Institute (NCI) | P3 | B |
| Cabozantinib | National Cancer Institute (NCI) | P3 | B |
| Nivolumab | National Cancer Institute (NCI) | P3 | B |
| Ipilimumab | National Cancer Institute (NCI) | P3 | B |
| Axitinib | M.D. Anderson Cancer Center | P2 | B |
+14 more in the Metastatic Malignant Neoplasm In The Lymph Nodes cohort
Other indications for Cyclophosphamide
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Adult Acute Lymphoblastic Leukemia | — | P4 | BBB · 79 |
| Mycosis Fungoides | — | P4 | BBB · 78 |
| B-Cell Childhood Acute Lymphoblastic Leukemia | — | P3 | BBB · 78 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Cyclophosphamide in Metastatic Malignant Neoplasm In The Lymph Nodes. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cyclophosphamide-metastatic-malignant-neoplasm-in-the-lymph-nodes-91638
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