Cytarabine
Acute Myeloid Leukemia And Myelodysplastic Syndromes Related To Alkylating Agent
Explore 3 assets in Acute Myeloid Leukemia And Myelodysplastic Syndromes Related To Alkylating Agent →Floatz Rating
BB64/100
Confidence
Indicative
Sponsor
National Cancer Institute (NCI)
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
49High confidence
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT01870596CT.gov Cytarabine With or Without SCH 900776 in Treating Adult Patients With Relapsed Acute Myeloid Leukemia | — | Completed | — | — | — |
NCT01132586CT.gov Lenalidomide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia | — | Completed | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Acute Myeloid Leukemia And Myelodysplastic Syndromes Related To Alkylating Agent
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Cytarabine (this asset) | National Cancer Institute (NCI) | P2 | BB · 64 |
| 2 (1H))-QUINOLINONE,6-(AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-4-(3-CHLOROPHENYL)-1-METHYL-,(+)- | National Cancer Institute (NCI) | P3 | BB |
| Azacitidine | National Cancer Institute (NCI) | P2 | BB |
| Caspofungin | Children's Oncology Group | P3 | BB |
| Fluconazole | Children's Oncology Group | P3 | BB |
| Lenalidomide | M.D. Anderson Cancer Center | P2 | B |
| Decitabine | Roswell Park Cancer Institute | P2 | B |
| Busulfanum | National Cancer Institute (NCI) | P2 | B |
| Tacrolimus | National Cancer Institute (NCI) | P2 | B |
+12 more in the Acute Myeloid Leukemia And Myelodysplastic Syndromes Related To Alkylating Agent cohort
Other indications for Cytarabine
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Acute Promyelocytic Leukemia | — | P4 | A · 82 |
| Adult Acute Lymphoblastic Leukemia | — | P4 | BBB · 79 |
| Acute Myeloblastic Leukemia With Maturation | — | P3 | BBB · 78 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
- 2 (1H))-QUINOLINONE,6-(AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-4-(3-CHLOROPHENYL)-1-METHYL-,(+)-National Cancer Institute (NCI)BB
- AzacitidineNational Cancer Institute (NCI)BB
- CaspofunginChildren's Oncology GroupBB
- FluconazoleChildren's Oncology GroupBB
- LenalidomideM.D. Anderson Cancer CenterB
Citation
Floatz Terminal. Cytarabine in Acute Myeloid Leukemia And Myelodysplastic Syndromes Related To Alkylating Agent. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/cytarabine-acute-myeloid-leukemia-and-myelodysplastic-syndromes-related-to-alkylating-agent
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