Floatz Rating
CC43/100
Confidence
Indicative
Sponsor
Sunnybrook Health Sciences Centre
Modality
UNKNOWN
Development Phase
Phase 1
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
28Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07179328CT.gov Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
89High confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Brain Glioblastoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Definity (this asset) | Sunnybrook Health Sciences Centre | P1 | CC · 43 |
| Disodium 4-((Tert-Butylimino)Methyl)Benzene-1,3-Disulfonate N-Oxide | Oblato, Inc. | P2 | B |
| Tvi-Brain-1 | TVAX Biomedical | P2/3 | B |
| Ruxolitinib | Baptist Health South Florida | P2 | CCC |
| Belinostat | Emory University | P2 | CCC |
| Avelumab | Clinique Neuro-Outaouais | P2 | CCC |
| Pembrolizumab | University Hospital, Geneva | P1/2 | CCC |
| Cis-Diamminedichloroplatinum Ii | Zhongnan Hospital | P1/2 | CC |
| ima950 | University Hospital, Geneva | P1/2 | CC |
+14 more in the Brain Glioblastoma cohort
Other indications for Definity
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Thyroid Cancer | — | P2 | CCC · 53 |
| Renal Cell Carcinoma | — | P2 | CCC · 51 |
| Breast Cancer | — | P2 | CCC · 50 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Definity in Brain Glioblastoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/definity-brain-glioblastoma
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