Floatz Rating
CCC52/100
Confidence
Indicative
Sponsor
Ohio State University Comprehensive Cancer Center
Modality
Small molecule
Development Phase
Phase 2
Status
Active
Evidence ledger · v0.2
Clinical Evidence
Clinical track record: trial progression, reported outcomes, safety signals, and endpoint quality.
37Indicative
Detailed axis rationale is planned and will be published soon.
| Trial | Phase | Status | N | Primary endpoint | Readout |
|---|---|---|---|---|---|
NCT07407647CT.gov Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer | — | Recruiting | — | — | — |
Competitive Position
Competitive setting: how crowded the indication is, class-level failures, and timing against rivals.
95Moderate confidence
Detailed axis rationale is planned and will be published soon.
Same indication · Vaginal Carcinoma
| Asset | Sponsor | Phase | Rating |
|---|---|---|---|
| Dehydroepiandrosterone (this asset) | Ohio State University Comprehensive Cancer Center | P2 | CCC · 52 |
| Durvalumab | M.D. Anderson Cancer Center | P2 | B |
| Ipilimumab | National Cancer Institute (NCI) | P2 | CCC |
| Dna Plasmid-Encoding Interleukin-12/Hpv Dna Plasmids Therapeutic Vaccine Medi0457 | M.D. Anderson Cancer Center | P2 | CCC |
| Plasmid Encoded Il-12 | M.D. Anderson Cancer Center | P2 | CCC |
| Nivolumab | National Cancer Institute (NCI) | P2 | CCC |
| Carboplatin | Case Comprehensive Cancer Center | P1 | CCC |
| Cis-Diamminedichloroplatinum Ii | National Cancer Institute (NCI) | P1 | CC |
| Recombinant Interleukin-12 | National Cancer Institute (NCI) | P1 | CC |
+10 more in the Vaginal Carcinoma cohort
Other indications for Dehydroepiandrosterone
| Indication | Sponsor | Phase | Rating |
|---|---|---|---|
| Postmenopausal Atrophic Vaginitis | — | P4 | BB · 66 |
| Systemic Lupus Erythematosus | — | P3 | BB · 66 |
| Breast Cancer | — | P4 | B · 61 |
Scientific Foundation
Strength of the underlying biology: target validation, tractability, modality fit, and how related mechanisms have fared.
NR
Planned for methodology v0.2.
Development Feasibility
How realistically the program can be executed, drawing on modality precedent, enrollment dynamics, and sponsor delivery.
NR
Planned for methodology v0.2.
Commercial Opportunity
Commercial prize: addressable population, unmet need, and the value case for the indication.
NR
Planned for methodology v0.2.
IP & Exclusivity
Exclusivity position, covering patent protection and freedom-to-operate runway.
NR
Planned for methodology v0.2.
Manufacturing & Supply
Manufacturing and supply readiness, driven by modality process and scale-up risk.
NR
Planned for methodology v0.2.
Related assets
Citation
Floatz Terminal. Dehydroepiandrosterone in Vaginal Carcinoma. Methodology v0.2. Rated under v0.2 effective July 8, 2026. Last refreshed July 8, 2026. Accessed July 14, 2026. https://terminal.floatz.ai/assets/dehydroepiandrosterone-vaginal-carcinoma
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